NAD+
Nicotinamide Adenine Dinucleotide
Endogenous dinucleotide coenzyme central to cellular redox biochemistry
5 papers · 2016–2022 · 5 journals
What the research explores
NAD+ sits at the intersection of energy metabolism and enzymatic signalling, which is why it recurs across so many research areas. Investigated topics include:
- The NAD+/NADH ratio as a readout of cellular redox state in cultured cells
- NAD+ as a required substrate for sirtuin deacetylases and PARP enzymes
- Salvage-pathway enzymology, particularly NAMPT-mediated regeneration from nicotinamide
- Compartment-specific nucleotide pools across cytosol, nucleus and mitochondria
- Analytical methods for quantifying nucleotide pools in cell and tissue lysates
These are areas of biochemical investigation described in the literature. Elements DNA makes no health, longevity or physiological claim of any kind and supplies this material for laboratory research use only.
References
A reference list, not evidence. Inclusion means a paper discusses the compound — not that it supports any use, and not that it describes this product.
2022
- NAD(+), Sirtuins and PARPs: enhancing oocyte developmental competence
Pollard CL, Gibb Z, Swegen A, et al.
The Journal of reproduction and development
- NAD(+), Sirtuins and PARPs: enhancing oocyte developmental competence
2018
- Niacin
Kirkland JB, Meyer-Ficca ML
Advances in food and nutrition research
- Metabolic networks in ferroptosis
Hao S, Liang B, Huang Q, et al.
Oncology letters
- Niacin
2017
- Roles of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase in Angiogenesis: Isoform-Specific Effects
Wang H, Hartnett ME
Antioxidants (Basel, Switzerland)
- Roles of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase in Angiogenesis: Isoform-Specific Effects
2016
- SIRT1 and Kidney Function
Guan Y, Hao CM
Kidney diseases (Basel, Switzerland)
- SIRT1 and Kidney Function
More research in longevity
For laboratory and research use only · Not for human or veterinary consumption · Not evaluated by the FDA