Elements DNA
Published research · Longevity

Glutathione

Endogenous tripeptide (gamma-Glu-Cys-Gly) studied in cellular redox biology

8 papers · 1990–2026 · 7 journals

What the research explores

Glutathione is among the most measured molecules in redox biology, appearing in research as both subject and reagent. Studied areas include:

  • The reduced-to-oxidised (GSH/GSSG) ratio as an index of cellular oxidative state
  • Glutathione peroxidase and glutathione reductase enzyme kinetics
  • Phase II conjugation reactions catalysed by glutathione S-transferases
  • Compartmental pools across cytosol, mitochondria and endoplasmic reticulum
  • Assay development for thiol quantification in cell and tissue lysates

These describe biochemical research topics reported in the literature. Elements DNA makes no detoxification, health or physiological claim and supplies this material for laboratory research use only.

References

A reference list, not evidence. Inclusion means a paper discusses the compound — not that it supports any use, and not that it describes this product.

  1. 2026

    1. Selenium-doped carbon dots nanozymes hitchhiking tailored liposomes block neuronal pyroptosis through GPX4/ROS/NLRP3/GSDMD axis to attenuate ischemic stroke

      Hou J, Yao L, Li Y, et al.

      Journal of nanobiotechnology

      PMID 41654881doi 10.1186/s12951-026-04107-9

  2. 2023

    1. Detection of Protein-Protein Interactions Using Glutathione-S-Transferase (GST) Pull-Down Assay Technique

      Gnanasekaran P, Pappu HR

      Methods in molecular biology (Clifton, N.J.)

      PMID 37450141doi 10.1007/978-1-0716-3327-4_10

  3. 2019

    1. Glutathione: subcellular distribution and membrane transport (1)

      Oestreicher J, Morgan B

      Biochemistry and cell biology = Biochimie et biologie cellulaire

      PMID 30427707doi 10.1139/bcb-2018-0189

  4. 2018

    1. Oxidative Stress Assessment in Zebrafish Larvae

      Domingues I, Gravato C

      Methods in molecular biology (Clifton, N.J.)

      PMID 29896710doi 10.1007/978-1-4939-7883-0_26

  5. 2015

    1. Benzene oxide is a substrate for glutathione S-transferases

      Zarth AT, Murphy SE, Hecht SS

      Chemico-biological interactions

      PMID 26554337doi 10.1016/j.cbi.2015.11.005

  6. 2001

    1. Serotonergic neurotoxicity of methylenedioxyamphetamine and methylenedioxymetamphetamine

      Monks TJ, Bai F, Miller RT, et al.

      Advances in experimental medicine and biology

      PMID 11764973doi 10.1007/978-1-4615-0667-6_62

  7. 1992

    1. The ATP-dependent glutathione S-conjugate export pump

      Ishikawa T

      Trends in biochemical sciences

      PMID 1455517doi 10.1016/0968-0004(92)90489-v

  8. 1990

    1. Bioactivation of hexachlorobutadiene by glutathione conjugation

      Dekant W, Vamvakas S, Anders MW

      Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

      PMID 2192968doi 10.1016/0278-6915(90)90041-k

More research in longevity

For laboratory and research use only · Not for human or veterinary consumption · Not evaluated by the FDA