NAD+
Nicotinamide Adenine Dinucleotide
Endogenous dinucleotide coenzyme central to cellular redox biochemistry
1 × $30 = $30. Applied in your cart.
- Every batch tested by an independent laboratory — identity by HPLC and mass spec.
- Dispatched on business days once payment has cleared. Free shipping over $100 — flat $10 otherwise.
- Discreet packaging, tracked and insured on every shipment.
For laboratory and research use only · Not for human consumption
- Certificate
- 99.99% purity
- Class
- Dinucleotide coenzyme, not a peptide
- Sizes
- 500mg · 1000mg
- Molecular weight
- 663.4 g/mol
- Form
- Lyophilised powder, sealed glass vial
- Storage
- Cool, dry and dark; refrigerate once reconstituted
Measured, not claimed.
Purity by HPLC
From this lot's own certificate, published exactly as the laboratory issued it.
- Lot
- 1500-501
- Tested
- Jun 30, 2026
- Laboratory
- Pacific Coast Biologics Inc
Measured on this lot
- Appearance
- Lyophilized Powder
- Identity Confirmation
- 9.0% Acetonitrile
- Molecular Formula
- C₂₁H₂₇N₇O₁₄P₂
- Molecular Weight
- 663.43 Da
Analysed against
- Identity
- HPLC + mass spec
- Purity
- HPLC · figure on the batch COA
- Net peptide content
- HPLC
- Heavy metals
- ICP-MS
- Sterility
- PCR
- Endotoxin
- USP <85>
What it is
NAD+, or nicotinamide adenine dinucleotide, is not a peptide but a dinucleotide coenzyme, and one of the most fundamental molecules in cellular biochemistry. It consists of nicotinamide and adenine nucleotides joined through their phosphate groups, and it cycles between oxidised (NAD+) and reduced (NADH) states as it shuttles electrons between metabolic reactions.
It ships as a lyophilised powder in a sealed glass vial, available in 500 mg and 1000 mg presentations. Each lot carries a Certificate of Analysis recording identity and purity. Supplied as a laboratory reference material for research use only, and not for human or veterinary use.
What the research explores
NAD+ sits at the intersection of energy metabolism and enzymatic signalling, which is why it recurs across so many research areas. Investigated topics include:
- The NAD+/NADH ratio as a readout of cellular redox state in cultured cells
- NAD+ as a required substrate for sirtuin deacetylases and PARP enzymes
- Salvage-pathway enzymology, particularly NAMPT-mediated regeneration from nicotinamide
- Compartment-specific nucleotide pools across cytosol, nucleus and mitochondria
- Analytical methods for quantifying nucleotide pools in cell and tissue lysates
These are areas of biochemical investigation described in the literature. Elements DNA makes no health, longevity or physiological claim of any kind and supplies this material for laboratory research use only.
Questions
How should the vial be stored?
Keep the sealed vial cool, dry and out of direct light before opening. Once in solution, store refrigerated and treat it as short-lived. Avoid repeated freeze-thaw cycles, which degrade the coenzyme.
How is the powder brought into solution?
Solvent is normally added slowly down the inside wall of the vial and dissolved by gentle swirling. Solvent choice, working concentration and protocol are determined by the researcher. We do not provide dosing or administration guidance of any kind.
What does the Certificate of Analysis cover?
The batch COA documents compound identity and chromatographic purity for the lot you receive, along with its lot identifier and test date. It characterises the material as supplied and is not a clinical or regulatory approval.
What arrives in the shipment?
One sealed glass vial of lyophilised powder in the size selected, protectively packaged and labelled with its batch identifier. Solvent and laboratory consumables are not included.
Which lot is NAD+'s published certificate for?
Lot 1500-501, measured 99.99% by HPLC, tested Jun 30, 2026, by Pacific Coast Biologics Inc. The full certificate, including the laboratory's own assay rows, is published at /coa/HX2OFHO7HR.
Literature
5 publications · 2016–2022
Peer-reviewed publications indexed on PubMed that discuss NAD+. Listed for reference only — inclusion is not a claim about this product or its effects.
- 2022NAD(+), Sirtuins and PARPs: enhancing oocyte developmental competence
Pollard CL, Gibb Z, Swegen A, et al. · The Journal of reproduction and development
PMID 36171094 · doi 10.1262/jrd.2022-052
- 2018Metabolic networks in ferroptosis
Hao S, Liang B, Huang Q, et al. · Oncology letters
PMID 29556292 · doi 10.3892/ol.2018.8066
- 2018Niacin
Kirkland JB, Meyer-Ficca ML · Advances in food and nutrition research
PMID 29477227 · doi 10.1016/bs.afnr.2017.11.003
- 2017Roles of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase in Angiogenesis: Isoform-Specific Effects
Wang H, Hartnett ME · Antioxidants (Basel, Switzerland)
PMID 28587189 · doi 10.3390/antiox6020040
- 2016SIRT1 and Kidney Function
Guan Y, Hao CM · Kidney diseases (Basel, Switzerland)
PMID 27536685 · doi 10.1159/000440967
Products are supplied strictly for laboratory and research use. They are not for human or veterinary consumption, and have not been evaluated by the U.S. Food and Drug Administration for the diagnosis, treatment, cure, or prevention of any condition.