NAD+ Nasal Spray

NAD+ is not a peptide. Nicotinamide adenine dinucleotide is a dinucleotide coenzyme — nicotinamide riboside joined to adenosine through a pyrophosphate bridge — and it is the oxidized partner in the NAD+/NADH couple that carries electrons through glycolysis, the TCA cycle and oxidative phosphorylation. It is also the substrate consumed by the sirtuin, PARP and CD38 enzyme families, which is why its cellular pool size is a common experimental readout.

This listing ships it already in solution: 1,000 mg of NAD+ in a sterile isotonic saline base, filled to 30 ml in a sealed bottle with a metered pump rated at approximately 120 actuations. NAD+ in water is hydrolytically sensitive, so the bottle is kept cold and sealed. Supplied for laboratory research use only.

NAD+ is one of the most studied molecules in cell biology, largely as a cofactor and a measurement rather than as an agent. Research areas include:

• Consuming enzymes — sirtuin deacetylation, PARP-mediated ADP-ribosylation and CD38 hydrolysis, all of which draw down the same pool.
• Salvage pathway chemistry — the routes from nicotinamide, nicotinamide riboside and NMN back to NAD+.
• NAD+/NADH ratio as a redox state indicator in metabolic assays.
• Analytical methods for quantifying intracellular pools, where sample handling dominates the result.
• Solution stability — hydrolysis and degradation kinetics in aqueous media.

Supplied as a reagent. We make no claim about outcomes in any organism.