Elements DNA
Published research · Hormone

CJC-1295 (No DAC)

Modified GRF (1-29) analogue studied for GHRH receptor signalling and stability

7 papers · 2005–2026 · 5 journals

What the research explores

The no-DAC form is used in the literature as a shorter-acting counterpart to DAC-conjugated GHRH analogues. Reported areas of study include:

  • Resistance to dipeptidyl peptidase-4 cleavage conferred by the substituted residues
  • GHRH receptor binding and cAMP generation in pituitary cell models
  • Half-life and exposure comparisons between DAC and no-DAC constructs in preclinical species
  • How stimulation frequency shapes somatotroph secretory patterns in animal models
  • Analytical separation of the intact peptide from its degradation products

These are published research directions rather than claims. Elements DNA makes no representation about effects in humans and supplies this material for in vitro and preclinical laboratory use only.

References

A reference list, not evidence. Inclusion means a paper discusses the compound — not that it supports any use, and not that it describes this product.

  1. 2026

    1. A new era of doping? Use of peptide and peptide-analog drugs in recreational and professional sport and bodybuilding: a critical review

      Coutinho LFD, DE Oliveira Neves LF, Camilo RP

      The Journal of sports medicine and physical fitness

      PMID 41880199doi 10.23736/S0022-4707.26.17773-1

  2. 2022

    1. Early detection of cannabinoids in biological samples based on their affinity interaction with the growth hormone secretagogue receptor

      Danila GM, Puiu M, Zamfir LG, et al.

      Talanta

      PMID 34736642doi 10.1016/j.talanta.2021.122905

  3. 2021

    1. Advances in the detection of growth hormone releasing hormone synthetic analogs

      Memdouh S, Gavrilović I, Ng K, et al.

      Drug testing and analysis

      PMID 34665524doi 10.1002/dta.3183

  4. 2019

    1. A method for confirming CJC-1295 abuse in equine plasma samples by LC-MS/MS

      Timms M, Ganio K, Steel R

      Drug testing and analysis

      PMID 30938069doi 10.1002/dta.2599

  5. 2016

    1. Netnography of Female Use of the Synthetic Growth Hormone CJC-1295: Pulses and Potions

      Van Hout MC, Hearne E

      Substance use & misuse

      PMID 26771670doi 10.3109/10826084.2015.1082595

  6. 2010

    1. Identification of CJC-1295, a growth-hormone-releasing peptide, in an unknown pharmaceutical preparation

      Henninge J, Pepaj M, Hullstein I, et al.

      Drug testing and analysis

      PMID 21204297doi 10.1002/dta.233

  7. 2005

    1. Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog

      Jetté L, Léger R, Thibaudeau K, et al.

      Endocrinology

      PMID 15817669doi 10.1210/en.2004-1286

More research in hormone

For laboratory and research use only · Not for human or veterinary consumption · Not evaluated by the FDA