Oxytocin

Oxytocin is studied heavily as a receptor ligand and as a structure-activity problem. Areas of study include:

• Oxytocin receptor pharmacology — a class A GPCR signaling through Gq and phospholipase C, read out as intracellular calcium flux.
• Selectivity against vasopressin receptors, where a two-residue difference produces substantial cross-reactivity and complicates interpretation.
• Structure-activity relationships of the cyclic ring — which substitutions preserve binding and which collapse it.
• Analog design for peptidase resistance, since the native peptide is cleared rapidly.
• Receptor distribution mapping in tissue sections across species.

Supplied as a characterized reagent. We make no claim about behavioural or physiological outcomes.