BPC-157
Pentadecapeptide of gastric origin, studied in tissue-repair models.
7 papers · 2011–2025 · 7 journals
What the research explores
BPC-157 appears in the preclinical literature chiefly as a subject of tissue-repair research. The published work is animal- and cell-model based, and the peptide has no approved application in humans.
Areas investigators have examined:
- Tendon, ligament and muscle repair models, including fibroblast migration and outgrowth in culture
- Angiogenesis, with particular attention to VEGFR2 signalling and the nitric oxide system
- Gastrointestinal mucosal integrity models, the context in which the parent sequence was first characterised
- Interaction with growth factor and neurotransmitter pathways in rodent studies
Findings across this body of work are preliminary and unevenly replicated. BPC-157 is supplied strictly as a laboratory research material.
References
A reference list, not evidence. Inclusion means a paper discusses the compound — not that it supports any use, and not that it describes this product.
2025
- Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing
McGuire FP, Martinez R, Lenz A, et al.
Current reviews in musculoskeletal medicine
- Multifunctionality and Possible Medical Application of the BPC 157 Peptide-Literature and Patent Review
Józwiak M, Bauer M, Kamysz W, et al.
Pharmaceuticals (Basel, Switzerland)
- Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing
2022
- Pentadecapeptide BPC 157 and the central nervous system
Vukojevic J, Milavić M, Perović D, et al.
Neural regeneration research
- Pentadecapeptide BPC 157 and the central nervous system
2021
- Stable Gastric Pentadecapeptide BPC 157 and Wound Healing
Seiwerth S, Milavic M, Vukojevic J, et al.
Frontiers in pharmacology
- Stable Gastric Pentadecapeptide BPC 157 and Wound Healing
2019
- Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing
Gwyer D, Wragg NM, Wilson SL
Cell and tissue research
- Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing
2018
- BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone Healing
Seiwerth S, Rucman R, Turkovic B, et al.
Current pharmaceutical design
- BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone Healing
2011
- The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration
Chang CH, Tsai WC, Lin MS, et al.
Journal of applied physiology (Bethesda, Md. : 1985)
- The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration
For laboratory and research use only · Not for human or veterinary consumption · Not evaluated by the FDA