AOD-9604

AOD-9604 is a modified fragment of human growth hormone corresponding to residues 176 to 191 of the C-terminal region, with a tyrosine added at the N-terminus. Because it reproduces only a short segment of the parent hormone rather than the full 191-residue chain, researchers use it to separate the behaviour of that fragment from the receptor activity of the intact protein.

The peptide ships as a lyophilised powder in a sealed glass vial in a 10 mg presentation. Each lot carries a Certificate of Analysis covering identity and purity. Supplied for laboratory research use only, and not for human or veterinary use.

Interest in AOD-9604 stems from a structural question: which activities of growth hormone are carried by the C-terminal fragment, and which require the intact protein. Published preclinical work explores:

• Lipid-metabolism signalling in isolated adipocyte and cell-culture systems
• Comparison of fragment behaviour against full-length growth hormone at the GH receptor
• Whether the fragment acts through pathways independent of the GH receptor
• Stability and degradation profiles of the shortened sequence relative to the parent hormone

These describe laboratory research topics, not outcomes. Elements DNA makes no claim regarding effects in humans or animals and supplies this material exclusively for in vitro and preclinical use.