Elements DNA
Published research · Metabolic

AOD-9604

Modified C-terminal fragment of human growth hormone, residues 176 to 191

7 papers · 2000–2017 · 5 journals

What the research explores

Interest in AOD-9604 stems from a structural question: which activities of growth hormone are carried by the C-terminal fragment, and which require the intact protein. Published preclinical work explores:

  • Lipid-metabolism signalling in isolated adipocyte and cell-culture systems
  • Comparison of fragment behaviour against full-length growth hormone at the GH receptor
  • Whether the fragment acts through pathways independent of the GH receptor
  • Stability and degradation profiles of the shortened sequence relative to the parent hormone

These describe laboratory research topics, not outcomes. Elements DNA makes no claim regarding effects in humans or animals and supplies this material exclusively for in vitro and preclinical use.

References

A reference list, not evidence. Inclusion means a paper discusses the compound — not that it supports any use, and not that it describes this product.

  1. 2017

    1. Human sports drug testing by mass spectrometry

      Schänzer W, Thevis M

      Mass spectrometry reviews

      PMID 26213263doi 10.1002/mas.21479

  2. 2016

    1. Simplifying and expanding the screening for peptides <2 kDa by direct urine injection, liquid chromatography, and ion mobility mass spectrometry

      Thomas A, Görgens C, Guddat S, et al.

      Journal of separation science

      PMID 26578461doi 10.1002/jssc.201501060

  3. 2015

    1. Detection and in vitro metabolism of AOD9604

      Cox HD, Smeal SJ, Hughes CM, et al.

      Drug testing and analysis

      PMID 25208511doi 10.1002/dta.1715

  4. 2014

    1. Identification and characterization of peptide drugs in unknown pharmaceutical preparations seized by the Belgian authorities: case report on AOD9604

      Vanhee C, Moens G, Deconinck E, et al.

      Drug testing and analysis

      PMID 24976118doi 10.1002/dta.1687

  5. 2013

    1. AOD-9604 does not influence the WADA hGH isoform immunoassay

      Orlovius AK, Thomas A, Schänzer W, et al.

      Drug testing and analysis

      PMID 24124033doi 10.1002/dta.1557

  6. 2004

    1. AOD-9604 Metabolic

      Wilding J

      Current opinion in investigational drugs (London, England : 2000)

      PMID 15134286

  7. 2000

    1. Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone

      Ng FM, Sun J, Sharma L, et al.

      Hormone research

      PMID 11146367doi 10.1159/000053183

For laboratory and research use only · Not for human or veterinary consumption · Not evaluated by the FDA