Elements DNA
Published research · Immune

Thymosin α-1

Acetylated 28-amino-acid thymic peptide studied in innate immune signalling

7 papers · 1992–2025 · 6 journals

What the research explores

Published research positions this peptide within innate immune receptor signalling. Investigated areas include:

  • Interaction with Toll-like receptors, particularly TLR2 and TLR9, in cultured immune cells
  • Dendritic cell maturation markers and cytokine expression profiles in vitro
  • T-cell differentiation readouts in cell-culture and rodent models
  • Signalling cascades downstream of pattern-recognition receptors
  • Analytical characterisation of the acetylated N-terminus and its contribution to stability

Every item above describes an area of laboratory investigation. None is a claim about treating, preventing or affecting any condition. Elements DNA supplies this peptide for in vitro and preclinical research only.

References

A reference list, not evidence. Inclusion means a paper discusses the compound — not that it supports any use, and not that it describes this product.

  1. 2025

    1. Aging and Thymosin Alpha-1

      Simonova MA, Ivanov I, Shoshina NS, et al.

      International journal of molecular sciences

      PMID 41373628doi 10.3390/ijms262311470

  2. 2024

    1. Enhanced Immunomodulatory Effects of Thymosin-Alpha-1 in Combination with Polyanionic Carbosilane Dendrimers against HCMV Infection

      Espinar-Buitrago MS, Magro-López E, Vázquez-Alejo E, et al.

      International journal of molecular sciences

      PMID 38396631doi 10.3390/ijms25041952

  3. 2023

    1. Thymosin alpha 1 restores the immune homeostasis in lymphocytes during Post-Acute sequelae of SARS-CoV-2 infection

      Minutolo A, Petrone V, Fanelli M, et al.

      International immunopharmacology

      PMID 36989892doi 10.1016/j.intimp.2023.110055

  4. 2007

    1. beta-Thymosins

      Hannappel E

      Annals of the New York Academy of Sciences

      PMID 17468232doi 10.1196/annals.1415.018

  5. 2001

    1. Thymosin alpha-1

      Ancell CD, Phipps J, Young L

      American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

      PMID 11381492doi 10.1093/ajhp/58.10.886

  6. 1999

    1. Homeostasis, thymic hormones and aging

      Goya RG, Bolognani F

      Gerontology

      PMID 10202264doi 10.1159/000022082

  7. 1992

    1. Thymic endocrinology

      Hadden JW

      International journal of immunopharmacology

      PMID 1618588doi 10.1016/0192-0561(92)90163-f

More research in immune

For laboratory and research use only · Not for human or veterinary consumption · Not evaluated by the FDA